Our proprietary testing solution is NGS platform-agnostic and delivers accurate, timely and robust results

Simple, streamlined NGS workflows
Providing actionable clinical treatment decisions

Pillar Biosciences NGS Technology Platform

Pillar oncoReveal workflow

Accurate amplification

SLIMamp single-tube multiplexing vs conventional
multiplexing

Western blot of how Pillar Biosciences' SLIMamp 2-plex w/ tagged primer pairs compairs to conventional 2-plex w/ primer pairs and a mix of amplicons 1&2. SLIMamp identfies both amplicons, while the conventional 2-plex just recognizes an overlapping amplicon.

High correlation between oncoRevealâ„¢ Multi-Cancer Panel
and a comparator multi-cancer assay

Pillar Biosciences' oncoReveal Multi-Cancer Panel performs congruently with the VAF % of Competitor X with an R squared of .9336
Pillar Biosciences PiVAT bioinformatics worfklow: 1) Align to genome, 2) Local realignment, filtering, and read assembly, 3) Proprietary variant calling

PiVAT delivers reliable answers even for damaged samples
by reducing sequencing errors

Pillar Biosciences' Precise allele frequency detection from compromised FFPE

Formalin-compromised reference standards (Horizon Discovery) were
evaluated using the oncoReveal Lung and Colon Cancer Panel. N=10;
error bars=standard deviation

Pillar Biosciences, Inc.
9 Strathmore Rd
Natick, MA 01760

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